apex wrote: ↑13 Dec 2020 04:29
ReactoR wrote: ↑12 Dec 2020 23:52
Мексидол не от тромбозов, это ноотроп, такое на западе действительно не применяют, типа для "улучшения мозгового кровообращения", антигипоксии и пр. вуду.
Мексидол - вещь! Похмелье облегчает. Входит в десятку самых популярных лекарств в России.
Витаминчики группы B, особенно B6, делают примерно тоже самое, Мексидол это аналог витамина B6. что-то делает, а что и в какой степени, особенно по сравнению с B6, неизвестно, неизучено. Вроде нетоксичный препарат и то уже радует. Но, например, гипервитаминоз витамином B6 изучен, как и то что витамин B6 помогает в организму восстановливаться и бороться с инфекцией
Обзорчик
https://www.frontiersin.org/articles/10 ... 62051/full
Vitamin B6 and Pneumonia
In 1949, Leftwich and Mirick reported a preventive effect of vitamin B6 against viral infection (13). Mice fed a vitamin B6-deficient diet were more susceptible to infection of murine pneumonia virus than control mice. Shan et al. recently indicated that vitamin B6 administration remarkably inhibited LPS-induced systemic inflammation and acute pneumonia in mice (28). Key events linked to infection with respiratory viruses are associated with oxidative stress, inflammation, and subsequent lung injury. In fact, oral administration of anti-oxidants such as carnosine and N-acetylcysteine exerted beneficial effects on lung injury (29, 30). These suggest that vitamin B6 may ameliorate the severity of COVID-19 by exerting its anti-oxidative and anti-inflammatory actions in lung, a primary target organ for COVID-19 virus infection.
Vitamin B6 and Immune Function
Vitamin B6 supplementation improved immune function in both human and animal studies (10), and vitamin B6 deficiency led to impairment of various facets of immunity such as lymphoid atrophy and reduced lymphocyte numbers (12). It improves the immune response, causing increased antibody production, and enhances communicative interactions between cytokines and chemokines (31). Thus, its deficiency may lead to suppressed immunity predisposing patients to infections. A previous study has implicated the lipid mediator sphingosine 1-phosphate (S1P) in vitamin B6-mediated immune regulation (32, 33). S1P regulates cell trafficking, especially cell egress from organized lymphoid tissues in thymus, bone marrow, lymph nodes, and intestinal mucosa (33). Cell trafficking is determined by the S1P gradient through S1P production and degradation mediated by S1P lyase and S1P phosphohydrolase (33). Since S1P lyase requires PLP as a coenzyme for S1P degradation, its deficiency impairs S1P lyase activity and elevates S1P levels. This in turn impairs lymphocyte trafficking from lymphoid tissues and reduces lymphocyte numbers in the peripheral tissues (32, 33).
Возможно Мексидол просто менее активная форма витамина B6 и достаточно изменить диету или попринимать витаминов, в пределах разумного, конечно, он накапливается в организме
Мир это Выхухоль.